Una amina biògena són amines generades per éssers vius (p. ex.: tiramina, histamina, i altres diamines). Es produeixen en certs aliments com el peix blau. biogenetico adj biogenetisch adj biogenicamine n g βιογενής αμίνη f-ης i amina biogena f biogenes Amin nt biogeochemical cycle n g βιογεωχημικός κύκλοςm. O amină biogenă este o substanță biogenă din clasa aminelor. Sunt compuși pe bază de azot care se formează în principal în urma reacțiilor de.
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DR Healthcare has signed cooperation agreements with universities and scientific societies. The scientist at DR Healthcare play a key role in all stages of the research and development process, from inception of a new research program to the regulatory approval of a new biofunctional product. Our work uses the most advanced state of the art technologies to study the underlying mechanisms causing the pathology.
biogeba This knowledge is applied to the identification, design and trial of new biofunctional products with therapeutic potential. The centre is responsible for the planning and implementation of research and innovation programmes in two well differentiated product lines about DAO deficiency: Clinical diagnostic products related to the activity of diamine oxidase.
Amina biògena – Viquipèdia, l’enciclopèdia lliure
Is an alteration in the metabolism of food histamine that appears when Diamine Oxidase DAO enzyme activity is low, in other words, when for some reason there is a significant deficiency in the functional activity of the main enzyme in the metabolism of histamine.
The imbalance between ingested histamine and the histamine released from the histamine storage cells, and the capacity for histamine degradation, leads to histamine accumulation in plasma and the occurrence of adverse effects on health.
aina In healthy people, histamine taken with food amima degraded quickly by Diamine Oxidase DAO enzyme, but people with low functional DAO activity have the risk of suffering histamine intolerance or food histaminosis. Unlike food allergy, the occurrence of symptoms or adverse effects is not linked to the intake of specific food; not only can it be related to a wide variety of food with different histamine contents, symptoms can also occur even after the ingestion of products with low histamine levels.
This imposed considerable difficulty when establishing a maximum tolerable dose; in fact, there is no clear consensus on this value. Due to the wide variety of symptoms derived from DAO Deficiency, which represent chronic pathologies with a high prevalence in population, immediate research and advances on its origin and blogena treatments are required. It is not necessary for all symptoms to manifest, although most patients with low functional DAO activity present an average of three of those symptoms, being migraine the prevalent one.
Migraine and other vascular headaches. Gastrointestinal disorders, especially those associated with irritable bowel syndrome, such as constipation, diarrhea, satiety, flatulence or swollen feeling. Dermatological disorders such as dry skin, atopy or psoriasis.
Soft-tissue pains usually diagnosed as fibromyalgia Chronic fatigue In childhood and adolescence, DAO deficiency has been linked to attention deficit and hyperactivity disorder ADHD.
Histamine process within the organism:. Route of histamine amna the body In the metabolism of histamine, when it should be degraded by DAO enzyme in order to become N-acetyl aldehyde imidazole, an accumulation of the amine is produced due to the lack of enzyme in the intestinal mucosa cells.
Low enzyme activity causes the concentration of histamine, which comes from the food and is generally considered normal, not to be metabolized and a transepithelial permeation of exogenous histamine. This way, histamine enters the bloodstream increasing its plasma concentration and once located in blood it spreads throughout the body.
DAO Deficiency Is an alteration in the metabolism of food histamine that appears when Diamine Oxidase DAO enzyme activity is low, in other words, when for some reason there is a significant deficiency in the functional activity of the main enzyme anina the metabolism of histamine.
Differentiation of adverse effects In healthy people, histamine taken with food is degraded quickly by Diamine Oxidase DAO enzyme, but people with low functional DAO activity have the risk of suffering histamine intolerance or food histaminosis. The most frequent symptoms derived from DAO Deficiency are: Histamine process within the organism: Route of histamine in the body Route of histamine in the body In the metabolism of histamine, when it should be degraded by DAO enzyme in order to become N-acetyl aldehyde biogrna, an accumulation of the amine is produced due to the lack of enzyme in the intestinal mucosa cells.