The authors document the cytological features on fine-needle aspiration cytology of a chondroblastoma which appeared as a lytic lesion in the. Chondroblastoma is an uncommon benign cartilage producing neoplasm with a characteristic epiphyseal location. This report documents the. Chondroblastoma is a rare primary bone tumor of young people .. Fine needle aspiration cytology of chondroblastoma of bone. Cancer.

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Churchill Livingstone Elsevier, Fine needle aspiration cytology in the cytklogy of bone lesions. The radiological findings of cortical erosion, soft tissue extension and intra-tumoral calcification are also chondrolastoma for the diagnosis of chondrosarcoma as against CMF. An year-old-female presented with pain in left leg for last 1-month and progressively increasing swelling around the knee joint for last 15 days. The cells were oval, spindle to stellate with small oval nuclei and uniform dense chromatin.

X-ray feature combined with fine-needle aspiration cytology favoured the diagnosis of chondroblastoma, which was further confirmed by histopathological examination.

Cytological diagnosis of chondroblastoma: diagnostic challenge for the cytopathologist

Diagnostic cytological features of condroblastoma are sheet-like clusters of mononuclear cells, scattered osteoclast-like giant cells and focal chondroid matrix formation.

Jaffe HL, Lichtenstein L. A useful immunohistochemical marker for diagnosing chondroblastoma. She also gave history of trauma at the same site. chnodroblastoma

Fine needle aspiration cytology of chondroblastoma of the fibula

Giant chondroblastoma of the scapula with pulmonary metastases. Epiphysial chondroblastoma of bone. The chromatin was uniformly bland and no nucleolus was seen. Journal List J Cytol v. Here, we report cytomorphology in two cases of chondroblastoma confirmed by histopathology with a brief review of literature. Open in a separate window. In giant cell tumor, the mononuclear cells are spindle-shaped and occur in clusters.


Am J Pathol ; Though the age of the patient and location of the lesion in the given bone are key pieces of information, accurate and early diagnosis is a must for planning appropriate treatment.

Less common sites include ribs, vertebrae and the bones of skull and hands.

Sterling G, Cytolgy A. Chondroblastoma of a metacarpal bone mimicking an aneurysmal bone cyst: The histological diagnosis of typical chondroblastoma is not difficult due to their characteristic appearance with rounded or polygonal chondroblasts, multinucleated giant cells and eosinophilic chondroid extracellular matrix with focal chicken-wire calcification. Chap 16, Bone; cytooogy There was cortical destruction with extra-osseous extension of abnormal marrow signals abutting soft tissue and musculature namely peroneal, extensor digitorum longus, flexor hallucis longus, tibialis anterior and posterior, and soleus muscle.

Ann Diagn Pathol ; 7: Fine-needle aspiration cytology FNAC is an established cost-effective diagnostic tool for skeletal lesions. Their cytoplasm was dense with rounded well-defined borders. Conflicts of interest There are no conflicts of interest.

The past decade has witnessed the impressive use of FNAC in the diagnosis of bone tumors. Page views in Treatment Curettage and bone grafting was performed. Subsequent intralesional curetting was done with bone autografting. All the giant cell containing lesions fall under the differential diagnosis of chondroblastoma. Support Center Support Center. A brief review of literature is also undertaken.


Fine needle aspiration cytology in the management of cytolgy and tumor like lesions of bone. As against chondroblastoma, osteoclastic giant cells and calcification, though occasionally seen, are not prominent features of CMF. Correspondence to Dr Shagufta Qadri, moc. Rare Painful, often causes joint effusions and restricts joint mobility Sites: Fine needle aspiration cytology of chondroblastoma of bone.

Curettings comprised of friable, red-brown soft tissue masses with a gritty feeling on cutting.

Fine needle aspiration cytology of chondroblastoma of the fibula

Ultrastructure of cartilaginous tumors and S protein in the tumors. The chondroblasts were distributed singly in smears, had round to oval nuclei with indentation and lobulation, and fine evenly distributed chromatin. Related articles Chondroblastoma chondroblasts osteoclast-like giant cells temporomandibular. With reference to the histogenesis of chondroblastoma, chondromyxoid fibroma and mesenchymal chondrosarcoma. Another entity to differentiate from chondroblastoma is Langerhan’s cell histiocytosis LCH.

Chondroblastoma is a rare benign cartilaginous tumor typically seen in long bones, especially femur, tibia and proximal humerus.

Tohoku J Exp Med ; There was no history of local trauma, fever, bone pain or weight loss. Chondrobastoma of chondroblastoma was made on cytology. Chondroblastoma can affect people of all ages.

Histopathology revealed tumor composed of sheets of polyhedral chondroblasts with round to ovoid, indented and lobulated nuclei and thick sharply defined cell membrane.